Suboxone is a combination of Buprenorphine and Naloxone prescription used to treat opioid addiction. Also, the drug contains one part Naloxone in every four parts of Buprenorphine.
Buprenorphine belongs to a group of drugs called opioid partial agonists. It works to relieve the withdrawal symptoms of opiates. Meanwhile, Naloxone is a class of drugs referred to as opioid antagonists that work to reverse the effects of narcotics.
Also, doctors administer naloxone to people who are in active overdose and have a higher chance to die from their drug abuse. The drug works to remove the narcotics from the receptors thus stopping the overdose. It works effectively in respiratory distress and can wake the user.
Naloxone starts the withdrawal symptoms immediately and triggers a full withdrawal of the user. Meanwhile, the use of Buprenorphine can treat the withdrawal symptoms and break the cycle of relapse.
Suboxone subdues the euphoric effect in opioids even when users take another substance like heroin. It blocks the euphoric feeling which heroin produces. The drug can effectively treat addiction because of the two main chemicals.
According to the Food and Drug Administration, it is a long acting drug that medical practitioner can administer for opioid detoxification.
Like other medication, the outcome varies on the user’s overall health and their opioid use. To find out how long Suboxone block opioid, also varies on several factors like:
There are several reasons why users choose Suboxone detox over other detoxification programs. The drug blocks opiates and withdrawal symptoms. Also, Suboxone has a long half-life which makes eliminates cravings for longer periods compare to methadone and other detox programs.
Suboxone works in two significant ways. The first is that it binds the opiate receptors to immediately stop drug cravings. These receptors commonly generate euphoric high that the users get while under the influence of narcotics.
Binding the receptors fall under the job of buprenorphine because it is a partial opiate receptor agonist. The drug is stronger than heroin and any other opiates, this keeps the receptors busy regardless of other present opiates.
In the meantime, naloxone works to remove all opiate agonist from the receptors to allow buprenorphine to take effect. The two chemicals work together to stop opiate reaction or the feeling of euphoria. It then replaces the opiate with partial opiate to prevent withdrawal symptoms.
To fully grasp the length of time that Suboxone can block opioids, one must understand the meaning of half-life. In medical terms, half-life means the duration for a substance to decrease in half. It means that half-life is the length of time for the half of the drug to leave the body.
Reckitt Benckiser, the manufacturer of the drug Suboxone claimed that the drug has a total half-life of 24 to 42 hours. It’s the time that takes buprenorphine to leave the body. Meanwhile, naloxone contains a half-life of 2 to 12 hours, which takes about 48 to 84 hours before the body excretes the drug.
Suboxone can block opiates around 24 hours after the user takes the drug. Opioids are then partially blocked for approximately 64 hours. This duration depends on the dosage of Suboxone and duration of time taking the drug.
However, each individual has a unique genetic make-up and different drug abuse history. It is important to seek medical advised before taking this medication.
Dr. Vikram Tarugu, M.D, is the CEO of Detox of South Florida, Inc and medical professional focused on addiction. A veteran in the medical field with over 25 years of professional experience. He is a consultant for many South Florida Rehab centers. Patients travel from allover the US to seek his help with addiction and Hepatitis C treatment.
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